Benefits & Features
- Supports methylation, which maintains healthy neurotransmission, DNA synthesis and gene regulation1
- Provides all of the benefits of folic acid regardless of MTHFR genetic variations2ā”
- Supports cardiovascular, cellular and neuronal healthā”
- Available in 400 mcg and 1,000 mcg
- Offers MetafolinĀ®Ā L-5-MTHF, a naturally occurring, universally metabolised form of folate
- Made with high-quality ingredients backed by verifiable science
Indications
- Ages 18 and up
- Universally metabolised form of folateā”
Suggested Use
Folate 400
As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.
Folate 1,000
As a dietary supplement, take 1 capsule daily, with a meal.
Science & Research
Verifiable Science
This formula has MetafolinĀ®Ā L-5-methyltetrahydrofolate (L-5-MTHF), a naturally occurring, universally metabolised form of folate. Unlike folic acid, L-5-MTHF does not require activation by DHFR (dihydrofolate reductase) and MTHFR (methylene tetrahydrofolate reductase), enzymes thatare subject to functional and genetic variations that may reduce conversion efficiency.2-4ā”
References
- Gropper SS, Smith JL, Groff JL.Ā Advanced Nutrition and Human Metabolism.Ā 5th ed. Belmont, CA: Wadsworth; 2009.
- Prinz-Langenohl R, et al.Ā Br J Pharmacol.Ā 2009 Dec; 158(8): 2014-21.
- Seremak-Mrozikiewicz A.Ā Ginekol Pol.2013 Jul;84(7):641-6.
- Patanwala I, et al.Ā Am J Clin Nutr.Ā 2014 Aug;100(2):593-9.
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Additional Information
Warning
If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Storage
Store in a cool, dry place.
FREE FROM
Pure EncapsulationsĀ® products are formulated using high-quality, pure ingredients, FREE FROM unnecessary additives and many common allergens including:
Resources
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ā”These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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